Cardiovascular protection

Stearic Acid
Catalog No: CFN93165

Stearic Acid and its derivatives have been used as gelators in food and pharmaceutical gel formulations. Stearic Acid is a potent phosphatase 1B inhibitor, possibly causing an enhancement in the insulin receptor signaling to stimulate glucose uptake into adipocytes. Stearic Acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocytes, it also can reduce metastatic tumor burden.

alpha-Asarone
Catalog No: CFN93217

alpha-Asarone has antioxidant activity, it effectively reversed MDR by inhibiting P-gp function and expression. alpha-Asarone protects against Ang II-mediated damage of endothelial cells and may be developed to prevent injury to cardiovascular tissues. Alpha-asarone congeners as hypolipidemic agents, they appeared to be promising for the treatment of human hyperlipidaemia and thrombotic diseases.Alpha-asarone also attenuates depression-like behavior in nicotine-withdrawn mice.

Yangambin
Catalog No: CFN96416

Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibition the Ca2+ influx through voltage-gated Ca2+ channels. Yangambin has central nervous system activity, it presents a depressant activity in the open field, forced swimming and pentobarbital sleeping time tests.